Running and longevity

Running and Longevity

News

• DialyMail: Stop that binge jogging
• Long term study found slow joggers had the lowest rates of death
• Strenuous joggers were as likely to die as sedentary non-joggers
• Going jogging three times a week for no more than 2.4 hours is optimal
• Pace of the slow joggers corresponds to vigorous exercise and strenuous jogging corresponds to very vigorous exercise, researchers qualified
• ScienceDaily: Light jogging may be most optimal for longevity

Guidelines and Researches

• CDC: How much physical activity do you need?
• Schnohr (2015). Dose of Jogging and Long-Term Mortality: the Copenhagen City Heart Study.
• Mittlema (1993). Triggering of Acute Myocardial Infarction by Heavy Physical Exertion
• Cheng (2000): Physical activity and self-reported, physician-diagnosed osteoarthritis: is physical activity a risk factor?
• Cheng (2012): Prevalence of diagnosed arthritis and arthritis-attributable activity limitation among adults with and without diagnosed diabetes

Need more statins or not

Need More Statins or Not

2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults

Don’t Give More Patients Statins
Source: NYT by John Abramson and Rita Redberg

"ON Tuesday, the American Heart Association and the American College of Cardiology issued new cholesterol guidelines that essentially declared, in one fell swoop, that millions of healthy Americans should immediately start taking pills — namely statins — for undefined health “benefits.” " ...

New ACC/AHA/NHLBI Guidance on Lifestyle for CVD Prevention
Source: Medscape by Shelley Wood

ACC-AHA cardiovascular prevention guidelines drop cholesterol treatment goals
Source: Cardiology News Digital Network  by Elizabeth Mechcatie

Risk Calculator for Cholesterol Appears Flawed
Source: NYT by Gina Kolata
"Last week, the nation’s leading heart organizations released a sweeping new set of guidelines for lowering cholesterol, along with an online calculator meant to help doctors assess risks and treatment options. But, in a major embarrassment to the health groups, the calculator appears to greatly overestimate risk, so much so that it could mistakenly suggest that millions more people are candidates for statin drugs." ...

GRADE guidelines (Grades of Recommendation, Assessment, Development, and Evaluation)

GRADE guidelines (Grades of Recommendation, Assessment, Development, and Evaluation)

From Journal of Clinical Epidemiology (JCE)

JCE published some systemic recommendations/guidance for rating quality of evidence and grading strength of recommendations in healthcare on two issues. I combined these related linkages below:

JCE Volume 64, Issue 4

Standards, guidelines, and norms

Challenges in guideline methodology

GRADE guidelines: A new series of articles in the Journal of Clinical Epidemiology

GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables

GRADE guidelines: 2. Framing the question and deciding on important outcomes

GRADE guidelines: 3. Rating the quality of evidence

GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias)

JCE Volume 64, Issue 12

Evidence, (un)certainty, and clinical practice

GRADE: complex decisions

Strength of evidence and handling uncertainty: practical considerations and general observations

GRADE guidelines: 5. Rating the quality of evidence—publication bias

GRADE guidelines 6. Rating the quality of evidence—imprecision

GRADE guidelines: 7. Rating the quality of evidence—inconsistency

GRADE guidelines: 8. Rating the quality of evidence—indirectness

GRADE guidelines: 9. Rating up the quality of evidence

 

The 2009 ISPAD Clinical Practice Consensus Guidelines

The 2009 Clinical Practice Consensus Guidelines
By the International Society for Pediatric and Adolescent Diabetes

Here are the PDFs of chapters:

Chapter 1: Definition, epidemiology, diagnosis and classification

Chapter 2: Presentation and phases of diabetes

Chapter 3: Type 2 diabetes

Chapter 4: Monogenic diabetes

Chapter 4b: Management of cystic fibrosis-related diabetes

Chapter 5: Diabetes education

Chapter 6: The delivery of ambulatory diabetes care

Chapter 7: Assessment and monitoring of glycemic control

Chapter 8: Insulin treatment

Chapter 9: Nutritional management

Chapter 10: Diabetic ketoacidosis

Chapter 11: Hypoglycemia

Chapter 12: Sick day management

Chapter 13: Exercise

Chapter 14: Management of children with diabetes requiring surgery or fasting

Chapter 15: Psychological issues

Chapter 16: Adolescence

Chapter 17: Microvascular and macrovascular complications

Chapter 18: Other complications and associated conditions

New High-Risk Criteria for CVD in Women

 A JAMA article 

"... a paradigm shift from evidence based to effectiveness based,..."

A Update of American Heart Association Guildeline: Effectiveness-Based Guidelines for the Prevention of Cardiovascular Disease in Women—2011 Update

The CONSORT Statement Website

CONSORT, which stands for Consolidated Standards of Reporting Trials, encompasses various initiatives developed by the CONSORT Group to alleviate the problems arising from inadequate reporting of randomized controlled trials (RCTs).

The main product of CONSORT is the CONSORT Statement, which is an evidence-based, minimum set of recommendations for reporting RCTs. It offers a standard way for authors to prepare reports of trial findings, facilitating their complete and transparent reporting, and aiding their critical appraisal and interpretation.

The CONSORT Statement comprises a 25-item checklist and a flow diagram, along with some brief descriptive text. The checklist items focus on reporting how the trial was designed, analyzed, and interpreted; the flow diagram displays the progress of all participants through the trial.

Considered an evolving document, the CONSORT Statement is subject to periodic changes as new evidence emerges. This website contains the current definitive version of the CONSORT Statement and up-to-date information on extensions.

Guidelines for Reporting Observational & RCT Studies

• Strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies
• The CONSORT 2010 Statement is intended to improve the reporting of a randomized controlled trial (RCT), also on Annals of Internal Medicine 
• The flow diagram is intended to depict the passage of participants through an RCT. The revised flow diagram depicts information from four stages of a trial (enrollment, intervention allocation, follow-up, and analysis).