Friday, March 05, 2010

In memory of Dr. John Denis McGarry



Dr. Denis McGarry was a great teacher and sage. His lecture affects my way of thinking on diabetes. Unforgettable.
“In 1992, he published a famous paper in Science entitled “What if Minkowski Had Been Ageusic?” (1). In this paper he suggested that scientific concentration on abnormal glucose metabolism had masked the critical importance of abnormal fat metabolism, especially in type 2 diabetes. Subsequent to this paper there was a huge swing by investigators toward the key role of abnormal lipid metabolism in insulin resistance and lipotoxic damage to tissues as diverse as the heart and the β-cell of the pancreas.”

Please find the full article here.

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